safety acetyl tributyl citrate cairan cairan beracun tidak

SAFETY DATA SHEET Revision Date 04/25/2022 Version 6

Product name : Tributyl O-acetylcitrate Product Number : 388378 Brand : Aldrich CAS-No. : 77-90-7 1.2 Relevant identified uses of the substance or mixture and uses advised against Identified uses : Laboratory chemicals, Synthesis of substances 1.3 Details of the supplier of the safety data sheet Company : Sigma-Aldrich Inc.

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Acetyl Tributyl Citrate - Cosmetics Info

The safety of Acetyl Triethyl Citrate, Acetyl Tributyl Citrate, Acetyl Trihexyl Citrate and Acetyl Triethylhexyl Citrate has been assessed by the Cosmetic Ingredient Review (CIR) Expert Panel. The CIR Expert Panel evaluated the scientific data and concluded that these ingredients were safe as used in cosmetics and personal care products.

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Final report on the safety assessment of acetyl triethyl

Physiologic effects noted with intravenous delivery of Acetyl Triethyl Citrate or Acetyl Tributyl Citrate include dose-related decreases in blood pressure and intestinal muscular spasms. These ingredients were not genotoxic in bacterial or mammalian test systems.

Acetyl Tributyl Citrate. IMAGE SOURCE: PubChem. SEARCH PRODUCTS. FIND PRODUCTS WITH THIS INGREDIENT. Other Concerns. Multiple, additive exposure sources (low) SYNONYMS. 1,2,3-PROPANETRICARBOXYLIC ACID, 2- (ACETYLOXY)-, TRIBUTYL ESTER. 1,2,3PROPANETRICARBOXYLIC ACID, 2 (ACETYLOXY), TRIBUTYL ESTER.

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Safety Assessment of Acetyl Trialkyl Citrates as Used in

Dermal application was not toxic in rabbits. In a guinea pig maximization test, Acetyl Triethyl Citrate was a sensitizer whereas Acetyl Tributyl Citrate was not. Limited clinical testing of Acetyl Triethyl Citrate and Acetyl Tributyl Citrate was negative for both skin irritation and sensitization.

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Acetyl Tributyl Citrate | Drug Information, Uses, Side

Technical details about Acetyl Tributyl Citrate, learn more about the structure, uses, toxicity, action, side effects and more.

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Acetyl Tributyl Citrate, the Most Widely Used Phthalate

Acetyl tributyl citrate (ATBC) is a colorless, odorless liquid. Its water solubility is less than 0.002 g/100 mL, but it is soluble in organic solvents. DryPowder; Liquid|Liquid|colourless, slightly viscous liquid with very faint sweet herbaceous odour. Acetyl tributyl citrate is an organooxygen compound. It derives from a tetracarboxylic acid.

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Acetyltributylcitrate - Wikipedia

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Acetyl tributyl citrate, the most widely used phthalate

We found that four of eight FDA-approved plasticizers increased SXR-mediated transcription. In particular, acetyl tributyl citrate (ATBC), an industrial plasticizer widely used in products such as food wrap, vinyl toys, and pharmaceutical excipients, strongly activated human and rat SXR.

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SAFETY DATA SHEET Revision Date 04/25/2022 Version 6

Product name : Tributyl O-acetylcitrate Product Number : 388378 Brand : Aldrich CAS-No. : 77-90-7 1.2 Relevant identified uses of the substance or mixture and uses advised against Identified uses : Laboratory chemicals, Synthesis of substances 1.3 Details of the supplier of the safety data sheet Company : Sigma-Aldrich Inc.

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Analysis of the most appropriate risk management option (RMOA)

tributyl ester Acetyl tributyl citrate Type of substance ? Mono-constituent ? Multi-constituent ? UVCB Structural formula: 1.2 Similar substances/grouping possibilities The tributyl citrate (TBC, EC No 201-071-2) registrant proposed in its dossier a category approach with TEC, ATEC, ATBC and ATEHC (see FR RMOA on TBC). The read-

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Safety Assessment of Acetyl Trialkyl Citrates as Used in

The Skin Deep? scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern. Every product and ingredient in Skin Deep gets a two-part score – one for hazard and one for data availability. The safest products score well by both measures, with a low hazard rating and

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CPSC Staff Statement on University of Cincinnati Report

The metabolism of acetyl tributyl citrate was evaluated using groups of male rats (number of animals, weights, and strain not stated). Each animal received a single oral dose of 14C-acetyl tributyl citrate (dose not stated). At 48 hr post dosing, approximately 99% of the administered dose had been excreted either in urine (59% to 70%), feces

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Final Report on the Safety Assessment of Acetyl Triethyl

Abstract: Acetyl tributyl citrate (ATBC) is an (the Food and Drug Administration) FDA-approved substance for use as a pharmaceutical excipient. It is used in pharmaceutical coating of solid

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Acetyl tributyl citrate, the most widely used phthalate

In particular, acetyl tributyl citrate (ATBC), an industrial plasticizer widely used in products such as food wrap, vinyl toys, and pharmaceutical excipients, strongly activated human and rat SXR. ATBC increased CYP3A4 messenger RNA (mRNA) levels and enzyme activity in the human intestinal cells but not in human liver cells.

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Material Safety Data Sheet - Cole-Parmer

Material Safety Data Sheet Acetyl tributyl citrate ACC# 09794 Section 1 - Chemical Product and Company Identification MSDS Name: Acetyl tributyl citrate Catalog Numbers: AC375180000, AC375181000, AC375185000 Synonyms: Tributyl 2-acetylcitrate Company Identification: Acros Organics N.V. One Reagent Lane Fair Lawn, NJ 07410

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SAFETY DATA SHEET

SAFETY DATA SHEET Revision Date 26-Dec-2021 Revision Number 4 1. Identification Product Name Tributyl citrate Cat No. : AC421440000; AC421440010; AC421442500 CAS No 77-94-1 Synonyms Tri-n-butyl citrate; Citric acid, tributyl ester; 2-Hydroxy-1,2,3-propanetricarboxylic Recommended Use Laboratory chemicals.

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Safety Assessment of Acetyl Trialkyl Citrates as Used in

The DG Enterprise has now obtained from industry a risk assessment report on acetyl tributyl citrate (ATBC) as plasticizer used in children’s toys. The CSTEE has therefore received the following questions: 1. Is the CSTEE of the opinion that the risk assessment is of a good quality? 2.

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Pharmacokinetic Properties of Acetyl Tributyl Citrate, a

In particular, acetyl tributyl citrate (ATBC), an industrial plasticizer widely used in products such as food wrap, vinyl toys, and pharmaceutical excipients, strongly activated human and rat SXR. ATBC increased CYP3A4 messenger RNA (mRNA) levels and enzyme activity in the human intestinal cells but not in human liver cells.

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Pharmacokinetic Properties of Acetyl Tributyl Citrate, a

Abstract: Acetyl tributyl citrate (ATBC) is an (the Food and Drug Administration) FDA-approved substance for use as a pharmaceutical excipient. It is used in pharmaceutical coating of solid

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Tributyl Citrate - Cosmetics Info

Safety Resources What Is It? Citric acid is a weak acid that is widely found in both plants and animals. It is a natural ingredient that is common in citrus fruits, for example, lemon juice , which contains about 5-8 percent citric acid.

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Screening-Level Hazard Characterization Acetyl Tributyl

The rate of atmospheric photooxidation is moderate. Acetyl tributyl citrate is expected to have low persistence (PI) and low bioaccumulation potential (Bl). The environmental fate properties of acetyl tributyl citrate are provided in Table 2. Conclusion: Acetyl tributyl citrate is a liquid with moderate vapor pressure and moderate water solubility.

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