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(PDF) Cross-linking in hydrogels - a review - ResearchGate

In the present review, chemical cross-linking by free-radical, condensation, UV radiation, and small-molecule cross- linking are discussed in details and influences of rigidity, flexibility, hydrophilicity, and hydrophobicity of a cross-linker on polymer properties are discussed. Expand 82 PDF View 1 excerpt, cites background

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Cross-linking in Hydrogels - A Review

Various physiochemical properties of hydrogels endow them with distinct applications. In this review, we present the commonly used crosslinking method for hydrogel synthesis involving physical and chemical crosslinks and summarize their current progress and future perspectives.

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A Review of the Mechanism, Properties, and Applications of

In this review, we evaluated the chemical, physical, and biological methods of preparing hydrogels and introduced three common cross-linking enzymes and their principles for preparing hydrogels. This review introduced the applications and properties of hydrogels prepared by the enzymatic method and also provided some suggestions regarding the

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Cross-Linked Hydrogel for Pharmaceutical Applications: A Review

This review mainly focuses on the types of hydrogels based on cross-linking and; secondly to describe the possible synthesis methods to design hydrogels for different pharmaceutical applications. The synthesis and chemistry of these hydrogels are discussed using specific pharmaceutical examples.

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The Formation Mechanism of Hydrogels - PubMed

Although chemical cross-linking is a highly resourceful method for the formation of hydrogels, the cross-linkers used in hydrogel preparation should be extracted from the hydrogels before use, due to their reported toxicity, while, in physically cross-linked gels, dissolution is prevented by physical interactions, such as ionic interactions, hyd...

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A Brief Review on Cross-linking in Hydrogel | Research

Fig. 2 Overview of the Fe3+鈥揂lg hydrogel properties and applications. The present review pretends to focus and describe, for the first time, all aspects of the research on Fe 3+ -cross-linked alginate hydrogels (Fe 3+ 鈥揂lg). This review paper is divided into two main sections.

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A Review of the Mechanism, Properties, and Applications of

In the present review, chemical cross-linking by free-radical, condensation, UV radiation, and small-molecule cross- linking are discussed in details and influences of rigidity, flexibility, hydrophilicity, and hydrophobicity of a cross-linker on polymer properties are discussed. Expand 82 PDF View 1 excerpt, cites background

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Cross-Linked Hydrogel for Pharmaceutical Applications: A Review

In this review, we evaluated the chemical, physical, and biological methods of preparing hydrogels and introduced three common cross-linking enzymes and their principles for preparing hydrogels. This review introduced the applications and properties of hydrogels prepared by the enzymatic method and also provided some suggestions regarding the

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The Formation Mechanism of Hydrogels - PubMed

Although chemical cross-linking is a highly resourceful method for the formation of hydrogels, the cross-linkers used in hydrogel preparation should be extracted from the hydrogels before use, due to their reported toxicity, while, in physically cross-linked gels, dissolution is prevented by physical interactions, such as ionic interactions, hyd...

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Recent Advances in Hydrogels - ACS Publications

Methods for producing alginate hydrogels in macro- and nano-meter scales have been compiled in several reviews. 74 While these reviews are mainly focused on Ca 2+ 鈥揂lg synthesis, most of the reported techniques can be extended to other cross-linking ions by replacing the gelling bath solution (typically containing CaCl 2) for the one with the

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Hydrogels: potential aid in tissue engineering鈥攁 review

Biodegradable nature of hydrogels has created much interest for drug delivery systems. The original three-dimensional structure disintegrates into nontoxic substances to ascertain an excellent biocompatibility of the gel. Chemical cross-linking is the highly resourceful method for the formation of hydrogels having an excellent mechanical strength.

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